Jay Hagan has served as our chief executive officer and principal executive officer since May 2017. Mr. Hagan previously served as our chief operating officer, principal financial officer and principal accounting officer from January 2016 to May 2017. From June 2011 through December 2015, Mr. Hagan served as the executive vice president, chief financial officer and chief business officer of Orexigen Therapeutics, Inc. (“Orexigen”). From May 2009 to June 2011, Mr. Hagan served as Orexigen’s senior vice president, corporate development, strategy and communications. From September 1998 to April 2008, Mr. Hagan served as managing director of Amgen Ventures. Prior to starting the Amgen Ventures Fund, Mr. Hagan served as head of corporate development for Amgen Inc. (“Amgen”). Before joining Amgen, Mr. Hagan spent 5 years in the bioengineering labs at Genzyme and Advanced Tissue Sciences. Mr. Hagan previously served on the board of Aurinia Pharmaceuticals, Inc., from February 2018 to July 2023, and previously served on the board of directors of Zosano Pharma Corp, a publicly-traded biotechnology company, from May 2015 to May 2022. He received an M.B.A. from Northeastern University and a B.S. in Physiology and Neuroscience from the University of California, San Diego.